The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry Eye

The Effect of Topical 0.05% Cyclosporine Eye Drops on Post-refractive Surgery Dry Eye

The purpose of this study is to observe the effect of 0.05% cyclosporine eyedrops combined with artificial tears in patients with dry eyes after corneal refractive surgery and to observe the changes in ocular surface characteristics and tear inflammatory cytokines before and after treatment.

The purpose of this study is to observe the effect of 0.05% cyclosporine eyedrops combined with artificial tears in patients with dry eyes after corneal refractive surgery and to observe the changes in ocular surface characteristics and tear inflammatory cytokines before and after treatment. At the same time, this study further observed whether 0.05% cyclosporine eyedrops combined with artificial tear eyedrops were more beneficial to ocular surface repair and tear film homeostasis compared with traditional artificial tears alone.

Inclusion Criteria:

• Patients who suffering from dry eye after refractive surgery with age between 18 and 45 years old.
• Any gender.
• Provision of written informed consent.

Exclusion Criteria:

• active ocular infection, ocular inflammation, active ocular allergy, severe blepharitis or obvious inflammation of the eyelid margin.
• Pregnant and lactating women, or those planning a pregnancy over the course of the study.
• Uncontrolled systemic disease.
• Suffer from diseases that may affect corneal nerves, such as keratoconus, trigeminal neuralgia, allergic conjunctivitis, etc.