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| ID | Type | Description | Link |
|---|---|---|---|
| RF1MH124909 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Mental Health (NIMH) | NIH |
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This project will assess the feasibility of traveling wave transcranial alternating current stimulation (tACS) to modify working memory performance and large-scale brain connectivity in surgical epilepsy patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Stimulation Theta Group | Experimental | Participants will experience traveling wave transcranial alternating current stimulation over the fronto-parietal regions at 4 Hz (theta condition). |
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| Stimulation Beta Group | Experimental | Participants will experience traveling wave transcranial alternating current stimulation over the fronto-parietal regions at 23 Hz (beta condition). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transcranial alternating current stimulation | Device | Traveling wave transcranial alternating current stimulation will be applied at 4 Hz and 23 Hz over frontal and parietal brain areas in a randomized counterbalanced order. |
| Measure | Description | Time Frame |
|---|---|---|
| Electrophysiological outcomes | Changes in spectral power and coherence of the local field potentials during transcranial electric stimulation relative to no stimulation periods. | Immediate effect during stimulation |
| Working memory outcomes | Changes in working memory performance as measured with the N-back task (quantified with d-prime) during stimulation. | Immediate effect during stimulation |
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Inclusion Criteria:
Exclusion Criteria:
1. diminished capacity to consent;
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| Name | Affiliation | Role |
|---|---|---|
| Alexander Opitz, PhD | University of Minnesota | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Minnesota | Minneapolis | Minnesota | 55455 | United States |
De-identified data will be shared following the IRB guidelines and Data Sharing Policy for the National Institute of Mental Health (NOT-MH-19-033).
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| ID | Term |
|---|---|
| D065908 | Transcranial Direct Current Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D003295 | Convulsive Therapy |
| D013000 | Psychiatric Somatic Therapies |
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| D004191 | Behavioral Disciplines and Activities |
| D004597 | Electroshock |
| D011580 | Psychological Techniques |