State Dependence of Prefrontal Transcranial Magnetic Stimulation

State Dependence of Prefrontal Transcranial Magnetic Stimulation

The study will examine whether the benefits of brain stimulation on mental functioning can be enhanced if an individual is actively engaging the target brain networks while receiving brain stimulation. The study includes two separate sessions and people will complete either a cognitive task or a perceptual task while receiving transcranial magnetic stimulation. The study will measure change in brain function with EEG.

Inclusion Criteria:

• Age 18 - 65,
• healthy controls

Exclusion Criteria:

• Diagnosed psychiatric disorder
• Potential contraindications to EEG (e.g. visible scalp abrasions, non-removable hair extensions and/or hair styling that would impede proper EEG recording)
• Potential contraindication to TMS (as identified by the TMS safety screener)
• Any previous adverse reaction to TMS or MRI
• Diagnosed epilepsy or previously experienced a seizure
• Diagnosed neurological condition, such as stroke or tinnitus
• Experienced a head trauma that was diagnosed as concussion
• Current use of, or recent withdrawal from, medications that can increase the risk of seizure
• Currently pregnant
• Any metal in the head (excluding mouth)
• Any implanted medical device