Ketamine for Analgesia After Cesarean Section

Ketamine for Analgesia After Cesarean Section

In this prospective randomized trial, investigators compared the analgesic effect of subanesthetic dose of ketamine versus placebo in parturients undergoing cesarean section under spinal anesthesia.

In this prospective randomized trial, investigators compared the analgesic effect of subanesthetic dose of ketamine versus placebo in parturients undergoing cesarean section under spinal anesthesia.

The patients were randomized in two groups:

• Group Ketamine: these patients recieved 0.25 mg/kg of Ketamin intravenously 5 minutes after the spinal anesthesia.
• Group Placebo: recieved 20 ml of normal saline solution intravenously 5 minutes after the spinal puncture.

The investigators recorded intra demographic, intraoperative and post operative data.

The main outcome was the analgesic score: the visual analog scale (VAS). dynamic VAS was also monitored at 24 hours post operatively.

Inclusion Criteria:

• full term pregnant adult patients
• Monofetal pregnancy
• scheduled for urgent or elective cesarean section under spinal anesthesia

Exclusion Criteria:

• necessity of general anesthesia during the procedure
• Post partum hemorrage