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| Name | Class |
|---|---|
| University of Calgary | OTHER |
| Lallemand Health Solutions | INDUSTRY |
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Proof of concept study to validate the ability of a capsule device to gather samples from the small bowel for microbiome analysis in adults and to detect dietary changes from simultaneous ingestion of a probiotic.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Single Arm | Experimental | Participant swallows and retrieves capsule in stool before and after ingestion of a probiotic. Capsule and stool samples are analyzed for presence of probiotic strain and compared to baseline. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ingestible Capsule | Device | Participants will swallow capsule and undergo X-rays to establish transit |
|
| Measure | Description | Time Frame |
|---|---|---|
| Bacterial density count | density count of probiotic strain compared between capsule and stool sample (CFU/ml) | 7 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Chris Andrews, MD MSc | University of Calgary | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cumming School of Medicine | Calgary | Alberta | T2N 4Z6 | Canada |
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| ID | Term |
|---|---|
| D019936 | Probiotics |
| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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| Probiotic | Dietary Supplement | Participants will swallow a probiotic capsule and the sample collection capsule at the same time to establish concentration of strain in small intestine. |
|
| D019602 |
| Food and Beverages |