Spontaneous coronary artery dissection (SCAD), is an underdiagnosed pathology, affecting predominantly young women without traditional cardiovascular risk factors and is associated with major adverse outcomes including myocardial infarction, cardiac arrest, or death.

Timely diagnosis of SCAD as well as clinical follow-up are of the essence in this pathology associated with major cardiac adverse outcomes. Despite recent improvements in diagnosis and recognition of the importance of SCAD, it remains poorly studied and understood.

In this context, we designed the SwissSCAD registry, a large, observational, prospective, cohort study, to describe the natural history of SCAD, its outcomes and its treatments.

Inclusion Criteria:

• Subject is ≥18 years of age.
• Patient presenting newly diagnosed SCAD or diagnosed with SCAD within the last 5 years.
• Subject must be willing to sign a Patient Informed Consent (PIC).

Exclusion Criteria:

• Patient unwilling or unable to provide informed consent.
• Patients with atherosclerotic or iatrogenic coronary dissection.

This observational study will recruit consecutive male and female patients presenting with newly diagnosed SCAD or having been diagnosed with SCAD within the last 5 years.

For the purposes of study inclusion, the definition of SCAD will be based on a central review of the coronary angiographic images confirmed by 2 independent assessors