Protective Effect of CoQ10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiovascular Surgery (PANDA V)

Protective Effect of Coenzyme Q10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiac and Aortic Surgery (PANDA V): a Randomized Controlled Trial

Cardiovascular diseases are the leading causes of death and prescription drug use. Research on certain dietary supplements looks promising as a way to help reduce risk factors. Previous studies showed that CoQ10 levels were decreased in cardiovascular patients and worsening of mitochondrial dysfunction was observed. The overall objective of this study is to determine if supplementing with CoQ10 can reduce inflammatory risk factors in adults with cardiac surgery, independent of other dietary or physical activity changes.

Inclusion Criteria:

• Adult men and women
• Who receive cardiovascular surgery
• Agree to participate in the surgery and sign the informed consent form

Exclusion Criteria:

• Pregnant or planning on getting pregnant during the study
• Contain a minimum of 2 traits of metabolic syndrome
• Refused to participate in the surgery and refused informed consent