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Determine whether supplementation with a combined dose of 20 g of hydrolyzed collagen and 50 mg vitamin C, along with a power training exercise program, increases rate of force development (RFD) and performance in athletes
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hydrolyzed collagen and Vitamin C powder mix | Experimental | 20 g hydrolyzed collagen + 50 mg vitamin C (ascorbic acid) pre-packed powder diluted in 250 ml (8 oz) of water |
|
| Maltodextrin powder | Placebo Comparator | 20 g maltodextrin pre-packed powder diluted in 250 ml (8 oz) of water |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Collagen and Vitamin C powder mix nutritional intervention | Dietary Supplement | 20 g collagen + 50 mg vitamin C daily, 60 min prior to exercise |
|
| Measure | Description | Time Frame |
|---|---|---|
| Maximal rate of force development (RFD) of isometric squat (MIS) | Force (N) over time (msec) for the maximum slope of the first 20% of the movement | % change from baseline to week 1, week 2 and week 3 |
| Counter-movement jump (CMJ) rate of force development (RFD) | CMJ jump performance N/s/kg | % change from baseline to week 1, week 2 and week 3 |
| Squat jump height rate of force development (RFD) | Squat jump height performance RFD/kg | % change from baseline to week 1, week 2 and week 3 |
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| Measure | Description | Time Frame |
|---|---|---|
| Maximum peak force of maximal isometric squat (MIS) | Peak force (N) | % change from baseline to week 1, week 2 and week 3 |
| Counter-movement jump (CMJ) net eccentric impulse | Jump performance max N/s/kg (Note: Eccentric is the drop down part of the CMJ) |
Inclusion Criteria:
Exclusion Criteria:
Collagen synthesis varies significantly throughout the menstrual cycle in females. This natural variation would confound the study. Provided this work proves successful, we will aim to perform similar studies in females.
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| Name | Affiliation | Role |
|---|---|---|
| Keith Baar, PhD | University of California, Davis | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UC Davis Functional Molecular Biology Laboratory and Human Performance Laboratory | Davis | California | 95616 | United States |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D003094 | Collagen |
| ID | Term |
|---|---|
| D001704 | Biopolymers |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
| D016326 | Extracellular Matrix Proteins |
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Sealed opaque packets coded by Sponsor's Product Development
| Maltodextrin placebo powder | Other | 20 g maltodextrin placebo daily, 60 min prior to exercise |
|
| Maximum power training exercise | Other | Explosive/power-based exercise training program 3 times/week at home consisting of drop jumps, box jumps, weighted jump squats loaded in a progressive manner weekly for 3 weeks. At baseline and at the end of each of the 3 weeks, measures of explosive performance are assessed in the lab (maximal isometric squat, counter-movement jump and squat jump) |
|
| % change from baseline to week 1, week 2 and week 3 |
| Counter-movement jump (CMJ) net concentric impulse | Jump performance max N/s/kg (Note: Concentric is the movement upwards of the CMJ) | % change from baseline to week 1, week 2 and week 3 |
| Leg stiffness assessment | Tendon stiffness mean per kg (N/m/kg) | % change from baseline to week 1, week 2 and week 3 |
| D012596 |
| Scleroproteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |