Alveolar Ridge Preservation Following Tooth Extraction Using Advanced Platelet Rich Fibrin (A-PRF) Versus Platelet Rich Fibrin (PRF)

Alveolar Ridge Preservation Following Tooth Extraction Using Advanced Platelet Rich Fibrin (A-PRF) Versus Platelet Rich Fibrin (PRF) A Randomized Clinical Trail :Comparative Study

the aim of this study is clinically and radiographically evaluate the use of advance platelet rich fibrin (A-PRF) versus platelet rich fibrin (PRF) in preservation of alveolar ridge following tooth extraction

systemically healthy patients who have at least one non-restorable tooth in the upper inter-bicuspid region and are not seeking immediate or early implant treatment will be allocated in this study after performing nonsurgical periodontal therapy and preoperative periapical therapy to evaluate and improve the condition of the periodontal tissues.

Anesthesia will be given then flapless atraumatic extraction using periotomes followed by forceps after luxation. For all groups, the socket will be debrided using curette then

• group A, the socket will be filled with A.PRF
• group B the socket will be filled with PRF.
• group C no bio-additive will be added.
• Criss cross horizontal mattress suture will be applied to close the extraction wound.

PRF and A-PRF preparation :

10 ml of blood will be drawn from each patient by vein puncture of the antecubital vein.

• Plateletr ich fibrin (PRF) is 3000 rpm and 10 minutes without addition of anticoagulant
• Advanced platelet rich fibrin (A-PRF) is 1300 rpm and 8 minutes.

Inclusion Criteria:

• Patients with at least one non restorable tooth in upper inter-bicuspid region.
• Stable periodontal condition with no acute periapical infection.
• Systematically healthy conditions.
• Cooperative patients.
• Intact buccal plate of bone.

Exclusion Criteria:

• Smokers.
• Patients seeking immediate or early implants.
• Pregnant females.
• Bone diseases.
• Drugs and diseases that may affect platelet count or function.