NIPE Monitoring Values During Routine Pediatric Anesthesia

Parasympathetic Activity Evaluation by Newborn Infant Parasympathetic Evaluation (NIPE) Monitor (MDMSTM, Loos, France) During Routine General Anesthesia in Children

Description of the standard values and fluctuations of the new NIPE index during routine pediatric anesthesia. NIPE monitor connected to anesthesia monitor, displays an instantaneous value ranging from 0 to 100. NIPE values described at different time points during anesthesia: beginning of induction, intubation, extubation, skin incision, opioid administration, vasopressors or atropine administration, transfusion, volume expansion. In addition, NIPE values during hemodynamic events (heart rate or blood pressure increase greater than 20%) will be recorded.

Inclusion Criteria:

• Surgery under general anesthesia
• Absence of analgesic treatment in the 24 hours before the intervention

Exclusion Criteria:

• Central or peripheral neuropathy
• Non sinus arrythmia, pace maker
• Cardiac surgery
• Analgesic medication within 24 hours before surgery
• Anti cholinergic or anti arrythmic chronic medication
• Opposition of the legal tutor or of the child