Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Multiple Sclerosis (ME) is a degenerative, inflammatory and autoimmune demyelinating disease of the central nervous system, characterized by demyelination due to inflammation and degeneration of the myelin sheaths enveloping nerves of the eye, periventricular grey matter, brain, spinal cord and brainstem. The symptoms associated with MS include symptomatic fatigue, muscle weakness, ataxia, mobility and balance problems or cognitive problems. Strength training has been shown to improve strength and mobility in persons with MS.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control Group | Active Comparator | Only testing sessions |
|
| Resistance training group | Experimental | Ten weeks of resistance training |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Resistance training | Other | Ten weeks of resistance training |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Maximal Voluntary Isometric Contraction of Knee Extension | Before the program training | |
| Maximal Voluntary Isometric Contraction of Knee Extension | After 10 weeks | |
| Rate of Force Development | Before the program training | |
| Rate of Force Development | After 10 weeks | |
| Central Activation Ratio | Before the program training | |
| Central Activation Ratio | After 10 weeks | |
| Spasticity | Pendulum test | Before the program training |
| Spasticity | Pendulum test | After 10 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Walking speed | Test 10 m-walks | Before the program training |
| Walking speed | Test 10 m-walks | After 10 weeks |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Jacobo Á Rubio-Arias, Dr | Universidad Católica San Antonio de Murcia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universidad Católica San Antonio | Murcia | 30107 | Spain |
The data will be published in a journal
After the completion of the study
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Testing sessions |
| Other |
Testing sessions |
|
| Static balance | Romberg Test with eyes open and closed. Analysis with force plates | Before the program training |
| Static balance | Romberg Test with eyes open and closed. Analysis with force plates | After 10 weeks |
| Functional capacity | Sit to stand test | Before the program training |
| Functional capacity | Sit to stand test | After 10 weeks |
| Heart Rate Variability | Sleeping Heart Rate Variability | Before the program training |
| Heart Rate Variability | Sleeping Heart Rate Variability | After 10 weeks |
| Sleep Quality | Karolinska Sleep Diary and Acelerometry | Before the program training |
| Sleep Quality | Karolinska Sleep Diary and Acelerometry | After 10 weeks |
| ID | Term |
|---|---|
| D009103 | Multiple Sclerosis |
| ID | Term |
|---|---|
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D055070 | Resistance Training |
| ID | Term |
|---|---|
| D005081 | Exercise Therapy |
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
| D005791 | Patient Care |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
Not provided
Not provided