Oral Steroid in Controlling Pain After TKA

Efficacy of Oral Corticosteroid in Controlling Pain After Total Knee Arthroplasty: A Randomized Controlled Trial

To compare efficacy of oral steroid in controlling pain after TKA

To compare pain and functional outcome for oral dexamethasone 16 mg, 8 mg and pacebo in patient undergoing unilateral primary total knee arthroplasy

Inclusion Criteria:

• Patients with osteoarthritis of the knee who undergoing unilateral TKA
• ASA class I-III
• Informed consent
• Good cognitive function

Exclusion Criteria:

• Uncontrolled DM (HbA1C > 7)
• Uncontrolled HT
• Morbid obesity (BMI > 40)
• History of bleeding in GI tract
• Corticosteroid used within 6 months
• Sever liver or renal impairments
• Studied drug allergy