A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy

A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy

The purpose of this research study is to understand more about various heart rhythms (electrical problems) in persons with hypertrophic cardiomyopathy with and without sleep apnea.

Adult patients with hypertrophic cardiomyopathy and without known atrial fibrillation or pacemaker/implantable cardiac defibrillation will undergo implantable loop recorder implantation. No direct interventions will be performed. Prospective observation of atrial and ventricular arrhythmia incidence and burden will be assessed, with additional analyses performed based on the presence or absence of obstructive sleep apnea.

Inclusion Criteria:

• Currently or previously enrolled in 17-003514 and 16-009474
• Adults age >18 years-old with a diagnosis of hypertrophic cardiomyopathy
• Both sexes
• Able to consent

Exclusion Criteria:

• Vulnerable study population
• Known atrial fibrillation or flutter (with the exception of post-operative atrial fibrillation)
• Pacemaker/ICD implantation
• Pregnancy