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This study aimed to investigate the effects of Game based dual-task training with treadmill on executive function and dual-task performance in individuals with early-onset PD and discuss the correlation between the change values of executive function and dual-task performance after training. Besides, investigate cortical activation after training.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Game based dual-task training group | Experimental | Participants in dual-task training group will execute game based dual-task training with treadmill, 3 times per week for 8 weeks |
|
| Treadmill training group | Active Comparator | Participants in treadmill training group will do treadmill training, 3 times per week for 8 weeks |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Game based dual-task training | Other | Participants in the experimental group will receive game based dual-task training with a treadmill |
|
| Measure | Description | Time Frame |
|---|---|---|
| Dual-task walking performance | To evaluate gait parameters while doing dual-task walking | Change from baseline at 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Single walking performance | To evaluate gait parameters while doing single walking | Change from baseline at 8 weeks |
| Timed up and go test | To evaluate functional walking ability |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yang Yearu, Ph.D. | Contact | +88628267279 | yryang@ym.edu.tw |
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| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| ID | Term |
|---|---|
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Treadmill training | Other | Participants in the control group will receive treadmill training |
|
| Change from baseline at 8 weeks |
| Parkinson's Disease Questionnaire 39 | To evaluate the quality of life | Change from baseline at 8 weeks |
| Frontal lobe battery test-Chinese version | To evaluate executive function | Change from baseline at 8 weeks |
| Trail-making test | To evaluate executive function | Change from baseline at 8 weeks |
| Stroop color and word test-Chinese version | To evaluate executive function | Change from baseline at 8 weeks |
| Verbal fluency test-Chinese version | To evaluate executive function | Change from baseline at 8 weeks |
| Digit span test | To evaluate executive function | Change from baseline at 8 weeks |
| Dual-task costs | To compare the cost between doing dual task and single task | Change from baseline at 8 weeks |
| Functional near-infrared spectroscopy | To evaluate the changes of blood perfusion in frontal lobe | Change from baseline at 8 weeks |
| D009069 | Movement Disorders |