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Data from a total of 2,500 walk-in or referred individuals who have been confirmed (diagnosed) HIV positive and accessing care and treatment services at the hospitals targeted by this study will be examined. The starting period for this project is estimated to be the last quarter (Q4) of fiscal year 2018.
This 24-month observation study will be conducted in 13 hospitals of 5 provinces in Thailand: Chiang Rai, Chiang Mai, Ubon Ratchathani, Chonburi, and Songkhla. The research team of TRCARC will collect and analyze secondary and de-identified data from the hospitals' databases. In each site, clients who agree to receive Same-Day ART service will go through standard of care procedures at each hospital, which include: post-test counseling and psychosocial support, baseline lab test, clinical screening, and physical examination. The drug regimen prescribed for clients will mirror the first line ART regimen in Thailand's national guideline, which is tenofovir (TDF), emtricitabine (FTC), and efavirenz (EFV). Retention of the clients will reflect that of the hospital's protocol, and CD4 and viral load will be tested according to the national guideline.
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| Measure | Description | Time Frame |
|---|---|---|
| Acceptance | Acceptance of Same-Day ART | 5 years |
| Type of Clients | Type of Clients (newly diagnosed or re-engaged) | 5 years |
| Number of clients categorized by demographic characteristics | Demographic Characteristics: age (years), gender (sex at birth and gender identity), risk behavior(s), and reason(s) for HIV testing | 5 years |
| Number of clients with each clinical characteristic | Clinical Characteristics based on Thailand's national guidelines (anti-HIV, creatinine, alanine transaminase, syphilis serology, hepatitis B antigen, hepatitis C antibodies, urinalysis, chest X-ray, CD4 count, CDC stage, comorbidity) | 5 years |
| Number of clients with each ART drug regimen differ from first line ART regimen | Drug regimen, if different from first line drug (TDF, FTC, EFV) | 5 years |
| Duration between date of HIV diagnosis and date of ART initiation | Duration between date of HIV diagnosis and date of ART initiation | 5 years |
| Number of clients with each clinical exclusion criteria | Clinical exclusion criterias : suspected TB, suspected cryptococcal meningitis, suspected serious OIs | 5 years |
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Inclusion Criteria:
Exclusion Criteria:
1. not Acceptance of Same-Day ART
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All persons who have tested HIV positive will be examined.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Thai Red Cross AIDS Research Centre | Pathum Wan | Bangkok | 10330 | Thailand | ||
| Wat Yannasangwararam Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34967504 | Derived | Seekaew P, Phanuphak N, Teeratakulpisarn N, Amatavete S, Lujintanon S, Teeratakulpisarn S, Pankam T, Nampaisan O, Jomja P, Prabjunteuk C, Plodgratoke P, Ramautarsing R, Phanuphak P. Same-day antiretroviral therapy initiation hub model at the Thai Red Cross Anonymous Clinic in Bangkok, Thailand: an observational cohort study. J Int AIDS Soc. 2021 Dec;24(12):e25869. doi: 10.1002/jia2.25869. |
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| ID | Term |
|---|---|
| D015658 | HIV Infections |
| ID | Term |
|---|---|
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D015229 | Sexually Transmitted Diseases, Viral |
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| Duration between date of ART initiation to date of being successfully transferred and date of ART continuation | Duration of linkage to care, if applicable (date of being successfully transferred and date of ART continuation) | 5 years |
| Retention | Retention (retention in care, discontinued ART, loss to follow-up, death) at month 1, month 3, month 6, and month 12 after ART initiation | 5 years |
| Viral load count | Viral load count (VL tested, percentage of VL suppressed, and dates of VL suppressed) | 5 years |
| Bang Lamung |
| Changwat Chon Buri |
| 00084 |
| Thailand |
| Queen Savang Vadhana Memorial Hospital | Chon Buri | Changwat Chon Buri | 20110 | Thailand |
| Sunpasitthiprasong Hospital | Udon Thani | Changwat Ubon Ratchathani | 34000 | Thailand |
| Hangdon Hospital | Hang Dong | Chiang Mai | 50300 | Thailand |
| Nakornping Hospital | Mae Rim | Chiang Mai | 50180 | Thailand |
| Sarapee Hospital | Saraphi | Chiang Mai | 50140 | Thailand |
| Hat Yai Hospital | Hat Yai | Song Khla | 90110 | Thailand |
| Sanpatong Hospital | Chiang Mai | 50120 | Thailand |
| Chiang Mai Hospital | Chiang Mai | 50300 | Thailand |
| Chiang rai prachanukor Hospital | Chiang Rai | 57000 | Thailand |
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |