Glycocalyx and Microcirculation in Sepsis

Association of Sublingual Microcirculation Parameters and Endothelial Glycocalyx Dimensions in Resuscitated Sepsis: A Cross-sectional Study

The aim of this observative, prospective study with cross-sectional design is to explore possible correlations/associations between microcirculation parameters and sublingual endothelial glycocalyx in sepsis. Therefore, 30 critically ill septic patients and 10 healthy controls were enrolled.

Inclusion Criteria - septic ICU cohort:

• Sepsis (based on sepsis-3 criteria)
• ICU stay

Inclusion Criteria - healthy controls:

- Adult healthy individuals

Exclusion Criteria (for all groups):

• Underage
• pregnancy
• oral mucosal inflammation or injury