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The aim of the study is to compare the effectiveness of conventional low flow anesthesia (LFA) with initial high fresh gas flow ( 4L/min) for 10 minutes and LFA with fixed fresh gas flow rate (1L/min).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Conventional group | Active Comparator | After standart intravenous anesthesia induction end endotracheal intubation desflurane vaporizer will be set at 6% with fresh gas flow rate 4 L/min (50% O2, 50% air) until the EtAA concentration reaches 0.7 MAC (minimum alveolar concentration) Then, the desflurane vaporizer will be at a 1% higher value than the EtAA concentration required to achieve 0.7 MAC. And after 10 minutes fresh gas flow rate will be reduced to 1L/min. |
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| Fixed Fresh Gas Flow Rate group | Active Comparator | After standart intravenous anesthesia induction end endotracheal intubation desflurane vaporizer will be set at 18% with fresh gas flow rate 1 L/min (50% O2, 50% air) until the EtAA concentration reaches 0.7 MAC (minimum alveolar concentration) Then, the desflurane vaporizer will be at a 2% higher value than the EtAA concentration required to achieve 0.7 MAC. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Conventional Low flow Anesthesia | Procedure | During the initial wash-in period 4 L/min Fresh gas flow will be used. |
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| Measure | Description | Time Frame |
|---|---|---|
| The time required to reach 0.7 MAC | perioperative | |
| number of adjustments made to the vaporizer settings | MAC will be held between 0.6-0.8 with adjustments at the vaporizer | perioperative |
| Measure | Description | Time Frame |
|---|---|---|
| anesthetic agent consumption | desfluane consumption at the first hour and at the end of the surgery wil be recorded | perioperative |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kahramanmaras Sutcu Imam University | Kahramanmaraş | In the USA Or Canada, Please Select... | 46100 | Turkey (Türkiye) |
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| Label | URL |
|---|---|
| Related Info | View source |
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| Low Flow Anesthesia with fixed fresh gas flow rate | Procedure | Fresh gas flow rate will be 1 L/min throughout the procedure. |
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