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The patients were randomized into two groups medium flow anesthesia (MeFA) and minimal flow anesthesia (MiFA). While MeFA received medium flow anesthesia with 2 lt/min, MiFA received minimal flow anesthesia with 0.5 lt/min fresh gas flow. In both groups dynamic compliance values, peak inspiratory pressure (PIP) values, total inhalation anesthetic drug consumption, total remifentanil drug consumption, duration of anesthesia, and duration of surgery were recorded. The FVC, FEV1, and FEV1/FVC values of the patients in both groups were evaluated and noted 24 hours before the operation, after the operation 2nd, 8th, and 24th hours.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Medium flow anesthesia | Experimental | After reaching the MAC 1 value with 4lt/min 50% O2 - 50% air and 8% desflurane medium flow anesthesia was started with 2 lt/min 50% O2 - 50% air with MAC 1 concentration desflurane. |
|
| Minimal flow anesthesia | Experimental | After reaching the MAC 1 value with 4 lt/min 50% O2 - 50% air and 8% desflurane minimal flow anesthesia was started with 0.50 lt/min 50% O2 - 50% air with MAC 1 concentration of desflurane. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Medium flow anesthesia | Other | Group MeFA; after reaching the MAC 1 value with 4lt/min 50% O2 - 50% air and 8% desflurane with remifentanil infusion, medium flow anesthesia was started with 2 lt/min 50% O2 - 50% air with MAC 1 concentration desflurane. The vaporizer was closed at the end of the last suture, and the flow was increased to 80% oxygen at 6 lt/min. |
| Measure | Description | Time Frame |
|---|---|---|
| Dynamic Compliance assessment | Dynamic Compliance will be assessed 5th minutes after endotracheal intubation | 5th minutes after endotracheal intubation |
| Dynamic Compliance assessment | Dynamic Compliance will be assessed 5th minutes after the surgical incision | 5th minutes after surgical incision |
| Dynamic Compliance assessment | Dynamic Compliance will be assessed 10th minutes after the surgical incision | 10th minutes after surgical incision |
| Dynamic Compliance assessment | Dynamic Compliance will be assessed 30th minutes after the surgical incision | 30th minutes after surgical incision |
| Dynamic Compliance assessment | Dynamic Compliance will be assessed 60th minutes after the surgical incision | 60th minutes after surgical incision |
| Dynamic Compliance assessment | Dynamic Compliance will be assessed immediately after the end of the surgical suturing | immediately after the end of the surgical suturing |
| Peak inspiratory pressure assessment | Peak inspiratory pressure will be assessed 5th minutes after endotracheal intubation | 5th minutes after endotracheal intubation |
| Measure | Description | Time Frame |
|---|---|---|
| FEV1 measures assessment | FEV1 measures assessment will be assessed 24 hours before the operation | 24 hours before the operation |
| FEV1 measures assessment | FEV1 measures assessment will be assessed 2nd hours after the operation |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Erkan Cem ÇELİK | Erzurum | 25080 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40826933 | Derived | Celik EC, Yayik AM, Aydin ME, Koksal ENM, Disci E, Kerget B, Doymus O, Ahiskalioglu EO, Ahiskalioglu A. Evaluation of lung dynamics and respiratory functions in patients undergoing minimal flow anesthesia: a prospective, randomized controlled trial. Med Gas Res. 2026 Jun 1;16(2):110-115. doi: 10.4103/mgr.MEDGASRES-D-25-00037. Epub 2025 Aug 18. |
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|
| Minimal flow anesthesia | Other | Group MiFA; after reaching the MAC 1 value with 4 lt/min 50% O2 - 50% air and 8% desflurane with remifentanil infusion, minimal flow anesthesia was started with 0.50 lt/min 50% O2 - 50% air with MAC 1 concentration of desflurane. The vaporizer was closed at the end of the last suture, and the flow was increased to 80% oxygen at 6 lt/min. |
|
| Peak inspiratory pressure assessment |
Peak inspiratory pressure will be assessed 5th minutes after the surgical incision |
| 5th minutes after the surgical incision |
| Peak inspiratory pressure assessment | Peak inspiratory pressure will be assessed 10th minutes after the surgical incision | 10th minutes after the surgical incision |
| Peak inspiratory pressure assessment | Peak inspiratory pressure will be assessed 30th minutes after the surgical incision | 30th minutes after the surgical incision |
| Peak inspiratory pressure assessment | Peak inspiratory pressure will be assessed 60th minutes after the surgical incision | 60th minutes after the surgical incision |
| Peak inspiratory pressure assessment | Peak inspiratory pressure will be assessed immediately after the end of the surgical suturing | immediately after the end of the surgical suturing |
| 2nd hour after the operation |
| FEV1 measures assessmentt | FEV1 measures assessment will be assessed 8th hours after the operation | 8th hour after the operation |
| FEV1 measures assessment | FEV1 measures assessment will be assessed 24th hours after the operation | 24th hour after the operation |
| FVC measures assessment | FVC measures assessment will be assessed 24 hours before the operation | 24 hours before the operation |
| FVC measures assessment | FVC measures assessment will be assessed 2nd hour after the operation | 2nd hour after the operation |
| FVC measures assessment | FVC measures assessment will be assessed 8th hour after the operation | 8th hour after the operation |
| FVC measures assessment | FVC measures assessment will be assessed 24th hours after the operation | 24th hour after the operation |
| FEV1/FVC measures assessment | FEV1/FVC measures assessment will be assessed 24 hours before the operation | 24 hours before the operation |
| FEV1/FVC measures assessment | FEV1/FVC measures assessment will be assessed 2nd hour after the operation | 2nd hour after the operation |
| FEV1/FVC measures assessment | FEV1/FVC measures assessment will be assessed 8th hour after the operation | 8th hour after the operation |
| FEV1/FVC measures assessment | FEV1/FVC measures assessment will be assessed 24th hour after the operation | 24th hour after the operation |
| ID | Term |
|---|---|
| D010349 | Patient Compliance |
| ID | Term |
|---|---|
| D010342 | Patient Acceptance of Health Care |
| D000074822 | Treatment Adherence and Compliance |
| D015438 | Health Behavior |
| D001519 | Behavior |
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