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| Name | Class |
|---|---|
| Dairy Management Inc. | INDUSTRY |
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This study will compare short-term post-exercise muscle glycogen synthesis following combined galactose-glucose, glucose alone or galactose alone ingestion.
Lactose, the sugar contained within milk, consists of glucose and galactose. Post-exercise consumption of a carbohydrate mixture containing glucose with galactose has been shown to accelerate liver glycogen repletion as compared to glucose-only provision. However, the extent to which galactose-glucose combinations influence post-exercise muscle glycogen storage has yet to be determined.
Therefore, this study will investigate whether short-term muscle glycogen storage after strenuous endurance exercise is enhanced by combined galactose-glucose or glucose only ingestion as compared to the ingestion of galactose alone.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Glucose alone | Experimental | Participants will complete a glycogen depleting bout of exercise followed by the provision of glucose-alone over 4 hours of recovery before a subsequent bout of exercise. |
|
| Galactose alone | Experimental | Participants will complete a glycogen depleting bout of exercise followed by the provision of galactose-alone over 4 hours of recovery before a subsequent bout of exercise. |
|
| Glucose and galactose | Experimental | Participants will complete a glycogen depleting bout of exercise followed by the provision of glucose and galactose over 4 hours of recovery before a subsequent bout of exercise. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Glucose alone | Other | Young men or women will complete a glycogen depleting bout of exercise followed by the provision of glucose-alone over 4 hours of recovery before a subsequent bout of exercise. |
| Measure | Description | Time Frame |
|---|---|---|
| Muscle glycogen synthesis rates (mmol/kg/dm/h) | Muscle glycogen synthesis rates over the post-exercise recovery period | 4 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Carbohydrate oxidation rates (g/min) | Total, exogenous and endogenous carbohydrate oxidation during a secondary bout of exercise | Up to 90 minutes |
| Fat oxidation rates (g/min) | Fat oxidation during a secondary bout of exercise |
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Inclusion Criteria:.
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Gareth Wallis, PhD | University of Birmingham | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| School of Sport, Exercise and Rehabilitation Sciences | Birmingham | West Midlands | B15 2TT | United Kingdom |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D005947 | Glucose |
| D005690 | Galactose |
| ID | Term |
|---|---|
| D006601 | Hexoses |
| D009005 | Monosaccharides |
| D000073893 | Sugars |
| D002241 | Carbohydrates |
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| Galactose alone | Other | Young men or women will complete a glycogen depleting bout of exercise followed by the provision of galactose-alone over 4 hours of recovery before a subsequent bout of exercise. |
|
| Glucose and galactose | Other | Young men or women will complete a glycogen depleting bout of exercise followed by the provision of glucose and galactose over 4 hours of recovery before a subsequent bout of exercise. |
|
| Up to 90 minutes |
| Plasma glucose (mmol/L) | Plasma glucose during the post-exercise recovery period and during a secondary bout of exercise | Up to 6 hours |
| Serum insulin (mU/L) | Serum insulin during the post-exercise recovery period and during a secondary bout of exercise | Up to 6 hours |
| Plasma galactose (mmol/L) | Plasma galactose during the post-exercise recovery period and during a secondary bout of exercise | Up to 6 hours |
| Plasma lactate (mmol/L) | Plasma lactate during the post-exercise recovery period and during a secondary bout of exercise | Up to 6 hours |
| Plasma non-esterified fatty acids (mmol/L) | Plasma non-esterified fatty acids during the post-exercise recovery period and during a secondary bout of exercise | Up to 6 hours |
| Plasma glycerol (umol/L) | Plasma glycerol during the post-exercise recovery period and during a secondary bout of exercise | Up to 6 hours |
| Plasma glucagon (pmol/L) | Plasma glucagon during the post-exercise recovery period and during a secondary bout of exercise | Up to 6 hours |