Objective Choroidal Thickness Measurements in Uveitis

Objective Choroidal Thickness Measurements During Intraocular Inflammation in Uveitis Using Optical Coherence Tomography

Optical Coherence Tomography (OCT) machines are non-contact instruments that can provide micrometer scale imaging of biological tissue. Applying the image processing allows us to automatically measure the choroidal thickness with good interclass correlation coefficient to the manual measurements.

Inclusion Criteria:

• To the control group - ability to perform OCT examination

• To the uveitis group - with one or more of the following clinical features (as indicators for active state of the disease):

  1. >1+ anterior chamber cells;
  2. >1+ vitreous haze;
  3. presence of vitreous cells;
  4. presence of blood in anterior chamber;
  5. presence of blood in vitreous;
  6. presence of aqueous or vitreous pigment.

Exclusion Criteria:

• To the control group - diagnosed uveitis

• In case of all groups:

  1. inability to give informed consent;
  2. inability to maintain stable fixation for OCT imaging.