Measurement of Anterior Chamber Cell Grading Using Ocular Coherence Tomography

Objective, Prospective Measurement of Anterior Chamber Cell Grading Using Anterior Chamber Ocular Coherence Tomography

Optical Coherence Tomography (OCT) is routinely used in ophthalmic clinical practice. It uses infrared light to image patient's eyes. Some patients, such as those with an inflammatory disease called uveitis or those who have just undergone cataract surgery, have intraocular inflammation. This intraocular inflammation commonly manifests as cells that can be seen on routine microscopic clinical examination. However, the only currently available method to quantify this intraocular inflammation is by manually counting on the microscopic clinical examination. The investigators plan to use the OCT machine to image patient's eyes. The investigators will then use the images obtained from the OCT to objectively quantify the degree of intraocular inflammation.

Inclusion Criteria:

• Age over 18 years old

• Intervention Arm:

  • Active anterior chamber inflammation in at least one eye as diagnosed by clinical exam
  • One of the following: 1) diagnosis of uveitis OR 2) undergone cataract extraction surgery within the previous 30 days

• Control Arm:

  • No active intraocular inflammation based on clinical exam

Exclusion Criteria:

• Corneal opacities in the affected eye
• Anyone judged unable to understand or consent to study participation