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The study was conducted to assess the impact of coenzyme Q10 and selenium on seminal fluid parameters and antioxidant status in infertile men.
The aim of this study was to assess the impact of coenzyme Q10 and selenium on seminal fluid parameters and antioxidant status in infertile men with idiopathic oligoasthenoteratospermia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Coenzyme Q10 | Active Comparator | Coenzyme Q10 200mg/day for 3 months |
|
| Selenium | Active Comparator | Selenium mcg/day for 3 months |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Coenzyme Q10 | Dietary Supplement | Coenzyme Q10 |
| |
| Selenium |
| Measure | Description | Time Frame |
|---|---|---|
| Semen volume (WHO 2010 guidelines) | Semen volume in ml | 3 months |
| Sperm concentration in semen (WHO 2010 guidelines) | Sperm concentration in million/ml | 3 months |
| Sperm motility in semen (WHO 2010 guidelines) | Sperm motility (%) | 3 months |
| Sperm morphology in semen (WHO 2010 guidelines) | Normal sperm morphology (%) | 3 months |
| Seminal plasma TAC (Colorimetric assays) | Seminal plasma total antioxidant capacity in mmol/ml | 3 months |
| Seminal plasma CAT (Colorimetric assays) | Seminal plasma catalase in U/ml | 3 months |
| Seminal plasma SOD (Colorimetric assays) | Superoxide dismutase in U/ml | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
Male infertility
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| Name | Affiliation | Role |
|---|---|---|
| Ahmed T Alahmar | University of Sumer, Iraq | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fertility Unit, Babyl | Hillah | 00964 | Iraq |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28771785 | Background | Alshahrani S, Aldossari K, Al-Zahrani J, Gabr AH, Henkel R, Ahmad G. Interpretation of semen analysis using WHO 1999 and WHO 2010 reference values: Abnormal becoming normal. Andrologia. 2018 Mar;50(2). doi: 10.1111/and.12838. Epub 2017 Aug 3. | |
| 29984205 | Background | Alahmar AT. The effects of oral antioxidants on the semen of men with idiopathic oligoasthenoteratozoospermia. Clin Exp Reprod Med. 2018 Jun;45(2):57-66. doi: 10.5653/cerm.2018.45.2.57. Epub 2018 Jun 29. |
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Patients data are anonymous and in hold with the principal investigator
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| ID | Term |
|---|---|
| D007248 | Infertility, Male |
| ID | Term |
|---|---|
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007246 | Infertility |
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| ID | Term |
|---|---|
| C024989 | coenzyme Q10 |
| D012643 | Selenium |
| ID | Term |
|---|---|
| D018011 | Chalcogens |
| D004602 | Elements |
| D007287 | Inorganic Chemicals |
| D008903 | Minerals |
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Parallel Assignment
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Open Label
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| Dietary Supplement |
Selenium |
|
| D052801 |
| Male Urogenital Diseases |