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| Name | Class |
|---|---|
| JiLin Women and Children Health Hospital | UNKNOWN |
| Shandong Provincial Hospital | OTHER_GOV |
| Shan Dong Qian Fo Shan Hospital | UNKNOWN |
| Shan Dong Liao Cheng Hospital |
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Eight hospitals in China will participate in the study, which aims to decrease the incidence of severe hyperbilirubinemia.
Through a prospective cohort study of healthy term and near-term infants, the study tries to truly reflect the epidemiology, intervention status, and outcomes of neonatal hyperbilirubinemia and the cost. Hopefully, by improving the quality of management of neonatal jaundice,we can explore and obtain a healthy term and near-term jaundice management model suitable for China's national condition, which can eventually reduce the incidence rate of neonatal severe hyperbilirubinemia and bilirubin encephalopathy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Before-intervention phase | No Intervention | All the healthy infants who were admitted from March 2018 to August 2018 to the Well Baby nurse of different hospitals. | |
| Intervention phase | Experimental | All the healthy infants who were admitted from September 2018 to February 2019 to the Well Baby nurse of different hospitals.During this phase,multiple intervention bundles of quality improvement will be implemented. |
|
| Sustainability intervention phase | Experimental | All the healthy infants who were admitted from March 2019 to August 2019 to the Well Baby nurse of different hospitals.In the Sustainability intervention phase,multiple intervention bundles of quality improvement will be continuous implemented. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Quality improvement of management of neonatal jaundice | Behavioral | During the Intervention phase and Sustainability phase ,The hospitals will receive training of multiple evidence based quality improvement methods. |
| Measure | Description | Time Frame |
|---|---|---|
| The incidence of bilirubin encephalopathy | 18 months |
| Measure | Description | Time Frame |
|---|---|---|
| The incidence of severe hyperbilirubinemia | Severe hyperbilirubinemia:total serum bilirubin more than 20mg/dL | 18 months |
| The rate of lost to follow-up | The rate of lost to follow-up for jaundice after discharge from well-baby nursery |
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Inclusion Criteria:
term or near-term neonates with gestational age ≥35w and birth weight ≥2000g.
Exclusion Criteria:
Infants admitted to a higher level of intervention before discharge.
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| Name | Affiliation | Role |
|---|---|---|
| Shuping Han, PHD | Nanjing Maternity and Child Health Care Hospital | Study Director |
| Zhangbin Yu, PHD | Nanjing Maternity and Child Health Care Hospital | Principal Investigator |
| Zhiyong Sun, PHD | JiLin Women and Children Health Hospital | Principal Investigator |
| Haiyan Cai, PHD | Qinhuangdao Maternal and Child Health Care Hospital | Principal Investigator |
| Yonghui Yu, MD | Shandong Provincial Hospital | Principal Investigator |
| Xin Yuan, MD | Shan Dong Qian Fo Shan Hospital | Principal Investigator |
| Jin Qian, MD | Shan Dong Liao Cheng Hospital | Principal Investigator |
| Jimei Wang, PHD | Obstetrics & Gynecology Hospital of Fudan University | Principal Investigator |
| Wenyan Tang, PHD | Jiangxi Maternal and Child Health Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nanjing Maternity and Child Health Care Hospital | Nanjing | Jiangsu | 210000 | China |
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| ID | Term |
|---|---|
| D051556 | Hyperbilirubinemia, Neonatal |
| D006932 | Hyperbilirubinemia |
| ID | Term |
|---|---|
| D007232 | Infant, Newborn, Diseases |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| UNKNOWN |
| Guangxi Maternal and Child Health Hospital | OTHER |
| Northwest Women's and Children's Hospital, Xi'an, Shaanxi | OTHER |
| Yin Chuan Maternity and Child Health Hospital | UNKNOWN |
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| 18 months |
| The incidence of adverse neurological outcomes in patients with severe hyperbilirubinemia | Patients with severe hyperbilirubinemia from 11 hospitals will be followed to investigate their neurological outcomes until 24 months after birth | 42 months |
| Medical costs in patients with severe hyperbilirubinemia | To compare the medical costs in patients with severe hyperbilirubinemia from 3 phases of quality improvement. | 18 months |
| Qiufen Wei, PHD | Guangxi Maternal and Child Health Hospital | Principal Investigator |
| Zhankui Li, PHD | Northwest Women's and Children's Hospital, Xi'an, Shaanxi | Principal Investigator |
| Jie Gu, PHD | Yin Chuan Maternity and Child Health Hospital | Principal Investigator |