Expiratory and Plasma Propofol Concentration in Gastrological Surgery Patients

Expiratory and Plasma Propofol Concentration in Bariatric and Cholecystectomy Patients

Determination of accuracy With Edmond (reg) expiratory propofol measurement Device, compared With concommitant plasma samples of propofol

Edmon (trade mark) is a New Device from BBraun, measuring the expiratory concentration of propofol in anaesthetized patients.

The investigators will test the accuracy and stability of such measurements in comparison With plasma propofol Levels.

The investigators will test during target Control infusion (Marsh model) and assumed stable plasma Levels.

Plasma samples of propofol will be taken for comparison With exhaled propofol.

Inclusion Criteria:

• • Patients admitted to Oslo University Hospital, scheduled for elective laparoscopic bariatric surgery or elective laparoscopic cholecystectomy.

  • Both genders.
  • Age 18-60 years, both inclusive.
  • BMI ≥ 20 kg/m2, 10 patients with BMI 20-30, and 10 patients with BMI > 40
  • ASA classification I-III

Exclusion Criteria:

• • Known hypersensitivity or other contraindication to propofol administered as Target Controlled Infusion.

  • Patients which during a preoperative visit are deemed not to tolerate propofol bolus or infusion as administered by Target Controlled Infusion.
  • Ongoing neuroleptic medication.