Breath Gas Measurement of Propofol During Anesthesia in Patients With Endourological Procedures

Study to Estimate Central Propofol Effect by Measuring Exhaled Propofol Concentrations in Patients

Propofol can be measured continuously in breath gas during anesthesia. This study compares propofol concentration in plasma and breath gas and processed electroencephalographic monitoring (bispectral index) under clinical conditions with patients and total intravenous anesthesia. Target controlled infusion technique is used to deliver adequate propofol concentration in plasma.

Inclusion Criteria:

• 18 years of age

• Written informed consent
• Ability and willingness to give written informed consent
• American Society of Anesthesiologists (ASA) risk score I-II

Exclusion Criteria:

• Denial of the patient
• Patients ASA physical status III- IV
• Pregnancy
• Volunteers with history of neurological disease or stroke
• Volunteers with a history of recreational drug abuse
• Volunteers with a history of alcohol abuse
• Known drug allergies
• History of adverse events during general anesthesia
• Total intravenous anesthesia not practicable