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Comparison between preemptive and postoperative intraarticular injection of tramadol on pain sensation after arthroscopy
220 patients assigned for therapeutic knee arthroscopy were divided into four equal groups in this prospective comparative study. All patients received IAI of 20 ml (0.5%) levopubivacaine alone in Group C; with 100 mg tramadol as PE (Group PE), at end of surgery (Group PO) or divided as 50 mg tramadol + 20 ml 0.25 % levobupivacaine as PE and 50 mg trmadol + 20 ml 0.25 % levobupivacaine as PO (Group PE/PO). Numeric rating scale (NRS) was used to assess pain sensation. Duration till request of rescue analgesia and number of requests were recorded. Patients' satisfaction concerning efficacy of PO analgesia was assessed using Iowa Satisfaction with Anesthesia Scale.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Levobupivacaine and tramadol Preemptive | Active Comparator | 20 ml 0.5% Levobupivacaine + 100 mg tramadol injected intraarticular preemptive. |
|
| Tramadol and levobupivacaine postoperative | Active Comparator | 20 ml 0.5% Levobupivacaine + 100 mg tramadol injected intraarticular postoperative. |
|
| Tramadol and levobupivacaine preemptive and postoperative | Active Comparator | 20 ml 0.25% Levobupivacaine + 50 mg tramadol injected intraarticular preemptive and postoperative. |
|
| Levobupivacaine | Active Comparator | 20 ml 0.5% Levobupivacaine only injected intraarticular preemptive. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Levobupivacaine Hydrochloride 2.5 MG/ML | Drug | Intrarticular injection of tramadol in addition to levobupivacaine in different doses preemptive and postoperative |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain control | Pain sensation after arthroscopy assessed by numeric rating scale depending upon patient facial appearance with severe patient expressing high score and no pain with lowest score | Pain assessment for 12 hours postoperative |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ain Shams University | Cairo | Egypt |
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| ID | Term |
|---|---|
| D000077554 | Levobupivacaine |
| D014147 | Tramadol |
| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 |
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|
| Aniline Compounds |
| D000588 | Amines |
| D003511 | Cyclohexanols |
| D000441 | Hexanols |
| D005233 | Fatty Alcohols |
| D000438 | Alcohols |
| D004123 | Dimethylamines |
| D008744 | Methylamines |
| D008055 | Lipids |