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Assessment of pulp inflammation by hemostasis achievement after pulp exposure
The possibility has been raised of diagnosing pulpal pathological status using the cytokines that are released during the inflammation process in healthy as well as infected tooth pulp. Cytokines are small polypeptides secreted by leucocytes and other inflammatory cells and are known to play important roles in the intensity and duration of the immune response
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| hemostasis achievement | in which hemostasis at the exposure site was achieved in five minutes were included in group A |
| |
| No hemostasis achievement | in which hemostasis at the exposure site couldn't be achieved in five minutes where included in group B |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ENzyme linked immunity-sorbet assays | Diagnostic Test | Hemostasis achievement reflecting inflammatory status of the pulp based on cytokine levels |
|
| Measure | Description | Time Frame |
|---|---|---|
| Measuring interleukin 2 (IL-2) | to measure cytokines levels after coronal pulpal removal | After 5 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Measuring interleukin 6 (IL-6) and interleukin 8 (IL-8) | to measure cytokines levels after coronal pulpal removal | After 5 minutes |
| Postoperative pain, Bifurcation/periapical radiolucency and Internal/external root resorption Or other pathological changes |
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Inclusion Criteria:
healthy children
patients had not used any inflammatory medications
primary molar teeth of these children were included based on the following clinical and radiographic criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo university | Cairo | Egypt |
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| ID | Term |
|---|---|
| D006470 | Hemorrhage |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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To assess postoperative pain by verbal questioning and To observe presence or absence of radiolucency and root resorption or pathological condition |
| 3,6,9,12 months |