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| Name | Class |
|---|---|
| Banoon IVF Center | OTHER |
| Qena Fertility Center | UNKNOWN |
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Using Latrunculin A and Ionomycin would improve the outcome of ICSI if the handling medium during the ICSI procedure has them.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ICSI medium supplemented with Ionomycin and Latrunculin A | Experimental |
| |
| ICSI medium as it is | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Doing ICSI I a medium supplemented with Ionomycin and Latrunculin A | Other | Ionomycin and Latrunculin A would activate oocyte during ICSI along with cytoskeleton stabilization for a favourable outcomes |
| Measure | Description | Time Frame |
|---|---|---|
| Fertilization rate | 6 days of culture |
| Measure | Description | Time Frame |
|---|---|---|
| Rates of Blastocyst formation and quality | Number of formed blastocysts and blastocysts with good-quality per fertilized oocytes | 6 days of culture |
| embryo utilization rate | 6 days of culture |
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Inclusion Criteria:
Exclusion Criteria:
-
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Qena Fertility Center | Qina | Qena Governorate | 123456 | Egypt | ||
| Banon Assiut |
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| ID | Term |
|---|---|
| D007246 | Infertility |
| ID | Term |
|---|---|
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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| ID | Term |
|---|---|
| D015759 | Ionomycin |
| C037067 | latrunculin A |
| ID | Term |
|---|---|
| D005231 | Fatty Acids, Unsaturated |
| D005227 | Fatty Acids |
| D008055 | Lipids |
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| clinical pregnancy rate | three months |
| ongoing pregnancy rate | 12 weeks |
| Asyut |
| Egypt |
| IbnSina IVF Center | Sohag | Egypt |