Evaluation of the Possible Relationship Between Periodontal Disease and Preterm Labor

Evaluation of the Possible Relationship Between Preterm Labor and Periodontal Disease With Clinical Periodontal, Biochemical and Microbiological Data

The primary objective of the study is to assess the incidence and severity of the periodontal infection of patients with preterm labor.

The secondary objective of the study is to analyze the relationship between preterm labor and periodontal infection, using clinical, biochemical and microbiological methods.

Preterm infants are born prior to completion of 37 weeks of gestation. Periodontal disease is a subclinical and persistent infection source which induces the systemic inflammatory reactions and increases the risk of preterm labor. It is believed that the results will set light to the etiology of preterm labor and will help to develop strategies to prevent the disease.

Inclusion Criteria:

• pregnant women with preterm labor
• 37. weeks of pregnant women with no history of preterm labor

Exclusion Criteria:

• Genitourinary infection
• pregnancy or pre-pregnancy hypertension
• HIV infection
• diabetes mellitus
• multiple pregnancy, preterm labor / low birth weight
• smoker and alcohol use history
• IVF pregnancy
• placental, cervical and uterine anomalies
• pregnancy with intrauterine growth retardation
• pregnancies with congenital or chromosomal fetal anomalies
• significant vaginal bleeding
• infertility stories
• drug addicts
• poor socioeconomic level