Maternal Periodontal Status and Cytokines in Preeclampsia

Maternal Periodontal Status and Gingival Crevicular Fluid Levels of Interleukin-6, Interleukin-35, and Interleukin-37 in Preeclampsia

Background: The purpose of this study is to examine the relationship between maternal preeclampsia and periodontal parameters and the correlation of these two disorders with maternal gingival crevicular fluid levels (GCF) of interleukin (IL)-35, interleukin-37 and interleukin-6. The investigators also investigated their relation to the severity of preeclampsia.

Methods: 82 preeclamptic women were recruited to the study (29 healthy pregnant women, 30 mild preeclamptic patient, 23 severe preeclamptic patient ). The clinical periodontal parameters and GCF samples were collected in the first day of puerperium.

Inclusion Criteria:

• Aged between 18 and 45 years
• 25 and 40 weeks of gestation.
• Healthy pregnants, mild and severe preeclampsia

Exclusion Criteria:

• Patients with accompanying diseases
• multiple gestations
• congenital abnormalities were excluded from the study.