Th17 Inducing Cytokines Pregnancy and After Postpartum

Interleukin-17 and Th17 Inducing Cytokines Exacerbate Periodontal Disease During Pregnancy and Postpartum

The aim of this study was to investigate salivary and gingival crevicular fluid (GCF) levels of IL-17A, IL-17E, IL-6 AND IL-23 during 2/3 trimester of pregnancy and after delivery.

IL-17 have a synergytic effect with IL-6 and IL-23. IL-17A levels elevated with periodontal diseases. Many systemical chronic conditions such as atherosclerosis and cardiovascular disease, pregnancy may contribute increasing of IL-17 family cytokine.

Inclusion Criteria:

• women 2 and 3 trimester of their pregnancy

Exclusion Criteria:

• any known systemic disease,
• periodontal treatment within the last six months,
• patients having less than 10 teeth,
• smokers,
• individuals with a BMI > 30 kg/m2,
• gestational diabetes and preeclampsia during pregnancy.