Systemic Organ Communication in STEMI | NCT03539133 | Trialant

Systemic Organ Communication in STEMI | NCT03539133 | Trialant

Arms/Interventions Module

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Left-ventricular function	LV-EF < 40% at 6 months Δ LV-EF ≥ 5% between day 5 of hospitalization and 6 months	6 months
Left-ventricular remodeling	Δ LVEDV ≥ 20% or Δ LVESV ≥ 15% between day 5 of hospitalization and 6 months	6 months
Myocardial texture	Infarct/Scar size > 17.9% or MVO (yes) or IMH (yes) on day 5 of hospitalization or at 6 months remote zone ΔECV between day 5 of hospitalization and 6 months	on day 5 of hospitalization and 6 months
Patency rate	Coronary patency rate	6 months

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Christian Jung, MD, PhD	Contact	+492118118800		christian.jung@med.uni-duesseldorf.de
Florian Bönner, MD,	Contact	+492118118800		florian.boenner@med.uni-duesseldorf.de

Overall Officials

Name	Affiliation	Role
Christian Jung, MD, PhD	Division of Cardiology, Pulmonary Disease and Vascular Medicine	Principal Investigator
Malte Kelm, MD	Division of Cardiology, Pulmonary Disease and Vascular Medicine	Study Chair

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
41791655	Derived	Helten C, Benkhoff M, Mourikis P, Metzen D, Barcik M, Hu H, Ayhan A, Haurand J, Alde K, Duse D, Jung C, Hohlfeld T, Levkau B, Petzold T, Borst O, Becher S, Ommer-Blaesius M, Witkowski S, Lang A, Cramer M, Dannenberg L, Kelm M, Gerdes N, Polzin A. Acetylsalicylic acid improves outcome after acute myocardial infarction by reducing thromboinflammation. J Thromb Haemost. 2026 Jun;24(6):2273-2292. doi: 10.1016/j.jtha.2026.02.003. Epub 2026 Mar 4.
39226457

Condition Browse Module