Active Matrix Metalloproteinase-8 (aMMP-8) Chair-side Test in Different Periodontal Disease

Evaluation of Active Matrix Metalloproteinase-8 (aMMP-8) Chair-side Test in Different Periodontal Disease and Healthy Implants

The aim of this study to evaluate the diagnostic accuracy of a new qualitative aMMP-8 POC test in different periodontal health and disease and as compared to the established quantitative laboratory method (ELISA)

MMP-8 has been reported to reflect the inflammatory status in periodontal tissues and, therefore represent as potential biomarkers of periodontitis. A positive aMMP-8 test could be an early indicator of these excessive and undesired tissue reactions.

Inclusion Criteria:

• Systemically healthy
• Nonsmokers

Exclusion Criteria:

• Participants were not included if they had systemic disease such as diabetes, cardiovascular.
• Participants who took regular medications that could affect of periodontal tissue
• Participants who received antibiotics less than 10 weeks before the study