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The study is a single-blind, randomised crossover study, investigating how a high glycaemic potato affects satiety in humans compared to a low glycaemic potato. This is done to shed further light on the discussion about whether potatoes with a high glycaemic index increases the risk of overweight and obesity and thus indirectly type 2 diabetes and cardiovascular disease.
The POSAT study follows a single-blinded randomized crossover design. Each subject will have two separate intervention days with at least a six-day washout period in between. On the two intervention days the subjects will be randomized into receiving a breakfast containing isocaloric amounts of either low or high GI potatoes. VAS will be measured 5 minutes before the meal, immediately after the meal is consumed and in intervals of 30 minutes thereafter until 2,5 hours after the initial meal. After this the subjects will be served a standardized homogenous ad libitum meal. The amount of food consumed will be registered. The subjects will be asked to fast for 8-10 hours prior to the trial days and abstain from vigorous physical activity and alcohol consumption for 2 days prior to each trial day. The trial will be conducted over a total of 8 days with 5-6 study subjects pr. trial day. The trial days will be spread out over a total of 2 weeks to allow for a 1-week washout period between trial days for each subject.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A | Experimental | Low glycaemic potato |
|
| B | Experimental | High glycaemic potato |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low glycaemic potato | Other | The Carisma potato variety is used as the low glycaemic index potato. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Subjective satiety evaluation | Visual Analogue Scale (100mm) filled out by subjects to describe satiety. | 3 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Hunger, fullness, and prospective food consumption | Visual Analogue Scale (100mm) filled out by subjects to describe hunger, fullness, and prospective food consumption. | 3 hours |
| Energy consumed in Ad libitum meal |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Anne Raben, Professor | Department of Nutrition, Sports and Exercise, University of Copenhagen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Copenhagen | Frederiksberg | 1958 | Denmark |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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Single-blind randomized crossover
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Subjets will not be aware of which test meal they will recieve first, and are not able to distinguish between the two potatoes.
| High glycaemic potato |
| Other |
The Arizona potato variety is used as the high glycaemic index potato. |
|
Energy intake (kJ) meassured by weighing of food consumed during a ad libitum meal.
| 30 minutes |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |