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Use of amniotic membrane(AMT) and platelet rich plasma (PRP) clot for closure of central corneal perforation
Use of amniotic membrane and platelet rich plasma clot for closure of central corneal perforation either post infective or posttraumatic
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Corneal perforation patients | Other | Patients who had/impeding corneal perforation due to melting of the cornea after infection with a corneal pathogen (bacterial or viral), with no previous surgical intervention. Patients will undergo: Platelet rich plasma clot implantation Wound closure with amniotic membrane |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Platelet rich plasma clot implantation | Procedure | Implantation of a platelet rich plasma clot, which is created from the plasma of the patients, and refrigerated to be inserted under the sealing amniotic membrane |
| Measure | Description | Time Frame |
|---|---|---|
| Closure of the corneal wound | sealing of the edges corneal gap, with formation of scar tissue | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ahmed A Abdelghany, MD | Assistant professor of Ophthalmology, Faculty of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine | Minya | Egypt |
steps of technique and results
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| ID | Term |
|---|---|
| D057112 | Corneal Perforation |
| ID | Term |
|---|---|
| D065306 | Corneal Injuries |
| D005131 | Eye Injuries |
| D005151 | Facial Injuries |
| D006259 | Craniocerebral Trauma |
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| Wound closure with amniotic membrane | Procedure | Closure of the corneal perforation with a synthetic amniotic membrane with a 2 mm safety margin |
|
| D020196 |
| Trauma, Nervous System |
| D009422 | Nervous System Diseases |
| D003316 | Corneal Diseases |
| D005128 | Eye Diseases |
| D014947 | Wounds and Injuries |