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Macular hole surgery were tried by different surgeons using many techniques with different successes but still there were many recurrences. In this study the investigators try to close these distinct types including recurrent holes using pre-prepared amniotic membrane.
It is an interventional study of using amniotic membrane graft for closure of macular hole associated retinal detachment in patient who had a previous failed macular surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Recurrent opened macular hole | Experimental | Pars plana vitrectomy with internal limiting membrane peel if not peeled in the first surgery and application of amniotic membrane graft |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Recurrent opened macular hole | Procedure | pars plana vitrectomy + internal limiting membrane peeling + Amniotic membrane graft placement over the hole + intraocular tamponade |
|
| Measure | Description | Time Frame |
|---|---|---|
| Anatomical restoration of macular hole closure | Closure of the macular hole | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Functional restoration after closure of the macular hole | Improvement of the best corrected visual acuity (BCVA) | 6 months |
| Functional restoration after closure of the macular hole | Any improvement of the waves in the electrophysiological (ERG) study. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Minia UNiversity hospital | Minya | Minya Governorate | 61111 | Egypt |
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| ID | Term |
|---|---|
| D012167 | Retinal Perforations |
| D012163 | Retinal Detachment |
| D009216 | Myopia |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
| D012030 | Refractive Errors |
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Individuals with recurrent macular hole associated retinal detachment
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| 6 months |