Efficacy of Platelet Enriched Plasma in Preventing Surgery for Patients With Chronic Tympanic Membrane Perforation

Efficacy of Platelet Enriched Plasma in Preventing Surgery for Patients With Chronic Tympanic Membrane Perforation

By doing this study, researchers hope to find out if platelet rich plasma (PRP) can heal holes in the eardrum as an alternative to surgery.

Inclusion Criteria:

• Patients who meet criteria for tympanoplasty procedure
• Willing to comply with the protocol and attend all study visits
• Able to provide written informed consent

Exclusion Criteria:

• Patients who have previously undergone middle ear or lateral skull base surgery
• Patients who would not qualify for a tympanoplasty
• Any type of platelet disorder, cancer, or ongoing systemic infection
• Any type of hemodynamic instability, septicemia, infection, tobacco use, any use of steroids to the ear drums
• Type I diabetes or other autoimmune pathology