The aim of this study is to systematically Analyse the metabolome in capillary blood of healthy men and women at rest and during defined standardized physical activity under normobaric normoxia or hypoxia with a specific focus on metabolites and metabolic pattern related to energy metabolism. The metabolome analyses in capillary blood could give us also or more detailed insight into erythrocyte metabolic physiology because it is known for a longer time that the primary metabolism of the erythrocyte reflects its Oxygen Saturation via the glycolytic metabolites / intermediates pattern.

Inclusion Criteria:

• healthy volunteers
• written informed consent

Exclusion Criteria:

• known cardio-vascular, lung, metabolic, endocrine, hematologic, kidney or neurologic diseases
• pregnancy, lactating period
• unability to understand study content and aims and to give written informed consent