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Opioid analgesics have many side effects. Quadratus lumborum (QL) block is one kind of regional nerve block that can reduce the side effects of opioid analgesics. The investigators hypothesize that QL block with local analgesics (ropivacaine) can significantly reduce pain intensity in comparison with placebo.
Opioid analgesics have been used to control the pain. However, many postoperative complication, such as nausea, vomiting, constipation, ileus, etc are related to opioid usage. Recently, local or regional pain nerve block, such as transversus abdominis plane block, wound infiltration, have been reported in several studies. Quadratus lumborum (QL) block was first introduced in the abstract of 2007 European Society of Regional Anesthesia. The effect is longer and more than that of transversus abdominis plane block because it works close to the spinal cord nerves. The QL block can be an effective pain control method for patients who underwent ileostomy closure. The aim of this study is to compare pain intensity after ileostomy closure between QL block (ropivacaine) group and placebo group (normal saline).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Quadratus lumborum block | Experimental | Quadratus lumborum block with 0.75% ropivacaine |
|
| Placebo | Placebo Comparator | Quadratus lumborum block with normal saline |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Quadratus lumborum block using ropivacaine | Procedure | After general anesthesia, an anesthesiologist will perform an quadratus lumborum block with 0.75% ropivacaine (20cc) under ultrasound guidance. |
| Measure | Description | Time Frame |
|---|---|---|
| Pain numerical rating scale (NRS) |
| 6 hours after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Pain NRS |
| 2, 12,24,36,48,72 hour after surgery |
| Rescue opioid analgesic requirement | Overall postoperative rescue of opioid analgesic requirement described by using the Defined Daily Dose |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jin Seok Yeo, MD | Kyungpook National University Chilgok Hospital | Study Director |
| In Teak Woo, MD | Kyungpook National University Chilgok Hospital | Study Chair |
| Soo Yeun Park, MD | Kyungpook National University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kyungpook National University Chilgok Hospital | Daegu | 41404 | South Korea |
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| ID | Term |
|---|---|
| D000077330 | Saline Solution |
| ID | Term |
|---|---|
| D000077324 | Crystalloid Solutions |
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |
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|
| Quadratus lumborum block with normal saline | Procedure | After general anesthesia, an anesthesiologist will perform an quadratus lumborum block with normal saline (20cc) under ultrasound guidance. |
|
| postoperative day 0,1,2,3 |
| Postoperative nausea and vomiting scale | Postoperative nausea and vomiting scores (assessed using a 0-2 categorical scale; no nausea/nausea/vomiting) | 2, 12,24,36,48,72 hour after surgery |
| Occurrence of prolonged post-operative ileus | Occurrence of prolonged post-operative ileus (assessed using a 0-1 categorical scale; no ileus/ ileus) | 8 weeks after surgery |
| Time to first oral fluid intake | Time to first oral fluid intake after surgery | 8 weeks after surgery |
| Time to first oral soft diet | Time to first oral soft diet after surgery | 8 weeks after surgery |
| Length of hospital stay | Length of hospital stay after admission | 8 weeks after surgery |