Quadratus Lumborum Block for Abdominoplasty

Quadratus Lumborum Block for Perioperative Analgesia in Patients Treated With Abdominoplasty: A Randomised Controlled Trial

Double blinded, randomized, controlled, phase IV intervention trial. Both groups will receive a quadratus lumborum Block (QL), using ropivacaine 3.75 mg/mL in the intervention group, and sterile sodium chloride in the control group. The aim of study is to investigate the effect of a QL Block on the perioperative pain during postbariatric abdominoplasty.

Inclusion Criteria:

• American Society of Anesthesiologists Physical Classification Status (ASA) I-II
• Age 18 to 64
• Weight above or equal to 60 kg
• Scheduled for post-bariatric surgery with standard full abdominoplasty performed by Dr Frøyen
• Patient is expected able to cooperate during the treatment and follow up.
• Signed informed consent obtained and documented according to the International Conference on Harmonization (ICH) good clinical practice (GCP), and national/local regulations.

Exclusion Criteria:

• A history of anaphylactic shock
• Cardiovascular disease other than hypertension and/or hyperlipidemia
• Known allergy to ropivacaine or morphine
• A history of chronic pain
• Psychiatric comorbidity
• Scheduled opioid pain medication or neuroleptic drugs
• Coagulation disorders or treatment with platelet inhibitors
• Pregnancy or breastfeeding
• Treatment with class III antiarrhythmics, sertindole, ziprasidone, amisulpride, ceritinib, hydroxyzine, fluvoxamine
• Any medical contraindication to the study intervention by the attending anaesthetist or surgeon (to be specified in screening form).