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The early diagnosis of Alzheimer's disease is essential to enable patients to have access to the available treatments. However, there is a delay between the diagnosis and the onset of symptoms, which can range from 1 year to more than 5 years. In clinical practice, the hippocampal volume, measured by the Scheltens index, is currently used as a marker of the progression of the disease.
The purpose of this study is to determine whether the patient's sex, age and ethnicity can influence the delay in the expression of cognitive troubles reported by the family at the first medical consultation, as well as to determine if there is a correlation between the delay reported by the family and the Scheltens index.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Alzheimer Disease | Alzheimer Disease patients admitted in the 'Memory Clinic' of the CHU Brugmann Hospital between 01-01-2010 and 31-01-2013. Diagnose according to the Dubois criteria |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Medical file data extraction | Other | Medical file data extraction |
|
| Measure | Description | Time Frame |
|---|---|---|
| Age | Age | Between 01-01-2010 and 31-01-2013 |
| Sex | Sex | Between 01-01-2010 and 31-01-2013 |
| Ethnic origin | Ethnic origin | Between 01-01-2010 and 31-01-2013 |
| Symptoms-diagnose time interval | Interval of time between the apparition of the first symptoms, as reported by the family, and the diagnose. | Between 01-01-2010 and 31-01-2013 |
| Scheltens scale | Evaluation of the hippocampal atrophy by means of magnetic resonance imaging. Scale from 0 (normal) to 4. | Between 01-01-2010 and 31-01-2013 |
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Inclusion Criteria:
Alzheimer Disease patients admitted in the 'Memory Clinic' of the CHU Brugmann Hospital between 01-01-2010 and 31-01-2013. Diagnose according to the Dubois criteria
Exclusion Criteria:
None
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Alzheimer Disease patients admitted in the 'Memory Clinic' of the CHU Brugmann Hospital between 01-01-2010 and 31-01-2013. Diagnose according to the Dubois criteria
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| Name | Affiliation | Role |
|---|---|---|
| Florence Benoit, MD | CHU Brugmann | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Brugmann | Brussels | Belgium |
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| ID | Term |
|---|---|
| D000544 | Alzheimer Disease |
| ID | Term |
|---|---|
| D003704 | Dementia |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| D024801 |
| Tauopathies |
| D019636 | Neurodegenerative Diseases |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |