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To assess whether brain creatine availability has an effect on cognition. To do so we will seek to increase brain creatine concentration via a creatine supplementation protocol.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Creatine supplementation | Experimental | 7-day creatine supplementation |
|
| Placebo supplementation | Placebo Comparator | 7-day calcium lactate supplementation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Creatine | Dietary Supplement | Participants will have to supplement themselves with creatine for 7 days (20g/day). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive performance - change in accuracy (%) during a 90-min cognitive task (i.e. Stroop task) | Accuracy (in %) will be assessed during a cognitive task, this cognitive task will be completed after both 7-day supplementation protocols (i.e. placebo and creatine) | During both lab visits (i.e. after both 7-day supplementation protocols); Accuracy (%) will be assessed during both lab visits with a 90-min cognitive task; Accuracy during the 90-min task will be reported as mean accuracy during 8 blocks of 11min15sec |
| Cognitive performance - change in reaction time (milliseconds) during a 90-min cognitive task (i.e. Stroop task) | Reaction time (in milliseconds) will be assessed during a cognitive task, this cognitive task will be completed after both 7-day supplementation protocols (i.e. placebo and creatine) | During both lab visits (i.e. after both 7-day supplementation protocols); Reaction time (RT) will be assessed during both lab visits with a 90-min cognitive task; RT during the 90-min task will be reported as mean RT during 8 blocks of 11min15sec |
| Measure | Description | Time Frame |
|---|---|---|
| Physical performance - reaction time (milliseconds) during a 7-min visuomotor reaction time task | Reaction time (in milliseconds) will be assessed during a visuomotor reaction time task, this physical task will be completed after both 7-day supplementation protocols (i.e. placebo and creatine) | During both lab visits (i.e. after both 7-day supplementation protocols); visuomotor reaction time will be assessed during both lab visits with a 7-min visuomotor reaction time task. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Human Physiology and Sports Physiotherapy Research Group | Brussels | Belgium |
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| ID | Term |
|---|---|
| D003401 | Creatine |
| C110051 | calcium lactate |
| ID | Term |
|---|---|
| D006146 | Guanidines |
| D000578 | Amidines |
| D009930 | Organic Chemicals |
| D000596 | Amino Acids |
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| Calcium lactate | Dietary Supplement | Participants will have to supplement themselves with calcium lactate for 7 days (elemental calcium: 0.780g/day). |
|
| D000602 |
| Amino Acids, Peptides, and Proteins |