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| Name | Class |
|---|---|
| Nutrabolt | INDUSTRY |
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This study was designed to examine how different forms of creatine impact active males.
This study examined the effects of different formulations of creatine nitrate on muscle creatine content, body composition, anaerobic exercise capacity, bench press performance and clinical chemistry panels in recreationally active males.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Creatine monohydrate | Experimental | Creatine monohydrate (6.0 g.) + dextrose (0.5 g.) |
|
| Creatine nitrate | Active Comparator | Creatine nitrate (5.0 g. creatine monohydrate + 1.5 g. creatine nitrate that provides 1.0 g. of creatine and 0.5 g. nitrate in 2:1 ratio). |
|
| Placebo | Placebo Comparator | 6.5 g. dextrose |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Creatine monohydrate | Dietary Supplement | Creatine monohydrate (6.0 g) + dextrose (0.5 g) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Effects of 28 Days of Different Forms of Creatine Supplementation on Body Water | Assessing Body Water through Bioelectrical Impedance Analysis (BIA) | 28 Days |
| Effects of 28 Days of Different Forms of Creatine Supplementation on Body Composition | Assessing Body Compositing through Dual-Energy X-Ray Absorptiometry (DXA) | 28 Days |
| Effects of 28 Days of Different Forms of Creatine Supplementation on intramuscular creatine | Assessing intramuscular creatine using standard spectrophotometric methods using a microplate spectrophotometer | 28 Days |
| Effects of 28 Days of Different Forms of Creatine Supplementation on intramuscular phosphocreatine | Assessing intramuscular phosphocreatine using standard spectrophotometric methods using a microplate spectrophotometer | 28 Days |
| Effects of 28 Days of Different Forms of Creatine Supplementation on intramuscular ATP | Assessing intramuscular Adenosine Triphosphate (ATP) using standard spectrophotometric methods using a microplate spectrophotometer | 28 Days |
| Effects of 28 Days of Different Forms of Creatine Supplementation on muscular strength | Assessing muscular strength through 1 Repetition Maximum (RM) testing | 28 Days |
| Effects of 28 Days of Different Forms of Creatine Supplementation on muscular endurance |
| Measure | Description | Time Frame |
|---|---|---|
| Effects of 28 Days of Different Forms of Creatine Supplementation on training volume (weight lifted x number of repetitions x number of sets) | Assessing training volume using a calculator | 28 Days |
| Effects of 28 Days of Different Forms of Creatine Supplementation on self-reported side effects |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Richard B Kreider, PhD | Texas A&M University | Principal Investigator |
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| ID | Term |
|---|---|
| D003401 | Creatine |
| ID | Term |
|---|---|
| D006146 | Guanidines |
| D000578 | Amidines |
| D009930 | Organic Chemicals |
| D000596 | Amino Acids |
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| Creatine nitrate | Dietary Supplement | Creatine nitrate (5.0 g creatine monohydrate + 1.5 g. creatine nitrate that provides 1.0 g. of creatine and 0.5 g. nitrate in 2:1 ratio) |
|
| Placebo | Dietary Supplement | Placebo (6.5 g dextrose) |
|
Assessing muscular endurance through repetition to failure testing
| 28 Days |
| Effects of 28 Days of Different Forms of Creatine Supplementation on anaerobic capacity | Assessing anaerobic capacity through 6 x 6 second sprints followed by a 30 second sprint on a Wingate bicycle ergometer | 28 Days |
Assessing self-reported side effects using a side effects questionnaire |
| 28 Days |
| Effects of 28 Days of Different Forms of Creatine Supplementation on blood | Measure standard clinical chemistry panels in the blood to evaluate safety | 28 Days |
| D000602 |
| Amino Acids, Peptides, and Proteins |