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Assessment of the quality of follicular fluid and early embryo via chemical markers.
The selectin of an embryo for transfer is currently based on detailed morphological assessment and scoring system. morhpokinetics introduced recently to IVF laboratories can define annotations and provide an algorithm for optimal cleavage rates and embryonic development. however more data and validations are requested when it comes to choosing the best single embryo from a cohort of available similarly graded embryos. Consequently, non-invasive quantitative methods for embryo selection prior to transfer have been sought. In the current study metabolic profile of follicular fluid and the embryos produced in IVF procedure will be assessed
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High and low grade embryos | The distribution for the high and low grade embryos is based on common morphological grading criteria. | ||
| High and low quality follicles | The distribution for the high and low grade oocytes is based on common morphological grading criteria and on different features of the participants such as age. |
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| Measure | Description | Time Frame |
|---|---|---|
| Different markers discriminating the studied groups. | High correlation between the studied markers and the currently used morphological assessment of the quality of embryos and oocytes will define the potential of the studied markers as a mean for embryo and quality assessment. The current study is pioneer in the field of assessment of embryos and follicles and this group of markers have not been studied previously, therefore we prefer not to clarify more details | two years |
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Inclusion Criteria:
Exclusion Criteria:
Participants are female patients undergoing IVF procedure in the IVF department in Carmel MC
Patients undergoing IVF procedures at Carmel Medical Center
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| Name | Affiliation | Role |
|---|---|---|
| Martha Direnfeld, Prof. | Carmel Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Carmel Medical Center | Haifa | 34362 | Israel |
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| ID | Term |
|---|---|
| D007246 | Infertility |
| ID | Term |
|---|---|
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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