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This study evaluates the effect of the need to void on parkinsonian gait
Parkinsonian syndromes are common causes of gait disorders, associated with hypometria, bradykinesia or rigidity. If motor disorders are the most visible part, lower urinary tract dysfunction is one of the most prevalent dysautonomic disorder (27-80%), especially over active bladder syndrome (OAB). If it seems evident that gait and urinary disorders are linked, because of similar anatomic pathways and control processes, no studies have investigated their association in extrapyramidal patients.
The aim of this study is to assess the effect of the need to void on the walking speed in this particular population.
This prospective study inclues all parkinsonian syndromes who had a follow-up for OAB. They must have a security delay over five minutes, no severe cognitive, motor or psychiatric disorders. We invite them to drink until a need to void (or equivalent). Bladder filling is measured by bladder scan, then they performe gait tests in a specific place, with calm and no passage : Patient can use their habitual walking device. Speed walk asking is comfortable for the two test. Three ten-meter tests, one double-task ten-meter test, one timed-up-and-go test, one timed raise of the floor (GMT). We repeat the same tests after voiding or self-catheterization. Toilets are just next to the hall where they realize the tests. A clinical examination assesses urinary dysfunction (USP, IPSS), motor score (UPDRS-III, Hoehn and Yahr scale, daily equivalent of levodopa), history of falls and comorbidities.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients enrolled | Patient with parkinsonian syndromes and lower urinary tract symptoms, age > 18, able to walk without human help on 50 meters, able to hold urine at least 3 minutes. A first record of gait speed will be at strong desire to void. A second record will be after voiding or catheterization Gait records consist on : 3x 10 meter walk test, 1x double task 10 meter walk test, 1x Timed up and Go test and 1x GMT |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gait speed | Other | No intervention, only propose water and wait for need to void |
|
| Measure | Description | Time Frame |
|---|---|---|
| Gait Speed | Gait speed calculated from 10 meter walk test. Time is recorded by a manual chronometer. 3 records are done, mean time is calculated. | [Time Frame: 1 Day: at strong desire to void and just after void] |
| Measure | Description | Time Frame |
|---|---|---|
| Time for Timed up and Go | 1 record is done for timed up and go test. Time is recorded by a manual chronometer | [Time Frame: 1 Day: at strong desire to void and just after void] |
| Time for GMT | 1 record is done for GMT , time is recorded by a manual chronometer |
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Inclusion Criteria:
Exclusion Criteria:
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Patients consulting in a tertiary center in neuro-urology
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| Name | Affiliation | Role |
|---|---|---|
| Gérard Amarenco, PhD | GREEN GRC-01, Neuro-urology, hôpital Tenon | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Neuro-urology, hôpital Tenon | Paris | France |
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| ID | Term |
|---|---|
| D059411 | Lower Urinary Tract Symptoms |
| D020734 | Parkinsonian Disorders |
| D020233 | Gait Disorders, Neurologic |
| ID | Term |
|---|---|
| D020924 | Urological Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001480 | Basal Ganglia Diseases |
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| ID | Term |
|---|---|
| D000072797 | Walking Speed |
| ID | Term |
|---|---|
| D005684 | Gait |
| D010808 | Physical Examination |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| [Time Frame: 1 Day: at strong desire to void and just after void] |
| Variation of gait speed | Standard deviation and Coefficient of variation is calculated from the 3 records of 10 meter walk test. | [Time Frame: 1 Day: at strong desire to void and just after void] |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D009461 | Neurologic Manifestations |
| D016138 |
| Walking |
| D008124 | Locomotion |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |