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Acute respiratory distress syndrome (ARDS) in neonates has been defined in 2017.
The death rate is over 50%.There are no special treatments for acute respiratory distress syndrome.
Acute respiratory distress syndrome (ARDS) is one of the serious complications in critically ill neonates. It can result in severe hypoxemia refractory to mechanical ventilation. There are few options for mechanical ventilation for such situations such as high frequency oscillation ventilation and extracorporeal membrane oxygenation. The aim of the present study is to determine whether transfusion of red blood cells can decrease the mortality in neonate with ARDS.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| RBC transfusion with conventional treatment | Experimental | Besides conventional treatment,neonates diagnosed with ARDS is treated with RBC transfusion. |
|
| conventional treatment | Active Comparator | neonates diagnosed with ARDS is treated with conventional treatment. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| conventional treatment with RBC transfusion | Other | Besides conventional treatment, neonates is given RBC transfusion. |
|
| Measure | Description | Time Frame |
|---|---|---|
| death rate | neonate died due to respiratory failure | within 100 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ma Juan, MD | Contact | 13508300283 | 476679422@qq.com | |
| Ma Juan, MD | Contact | 1388559467 | 476679422@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Shi Yuan, PhD,MD | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | Recruiting | Chongqing | Chongqing Municipality | 400042 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38780066 | Derived | Radford M, Estcourt LJ, Sirotich E, Pitre T, Britto J, Watson M, Brunskill SJ, Fergusson DA, Doree C, Arnold DM. Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support. Cochrane Database Syst Rev. 2024 May 23;5(5):CD011305. doi: 10.1002/14651858.CD011305.pub3. |
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| conventional treatment | Other | neonates is treated with conventional treatment. |
|
| ID | Term |
|---|---|
| D012128 | Respiratory Distress Syndrome |
| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D012120 | Respiration Disorders |
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