Heliox for Neonate With Acute Respiratory Distress Syndrome (ARDS)

Heliox for Neonate With Acute Respiratory Distress Syndrome (ARDS): A Randomized Controlled Trial

Acute respiratory distress syndrome (ARDS) in neonates has been defined, the role of heliox is not clear.This study aimed to determine whether ARDS neonate would benefit from heliox when oxygenation deteriorated on mechanical ventilation and to identify any potential risk factors related to mortality.

Acute respiratory distress syndrome (ARDS) can result in severe hypoxemia refractory to mechanical ventilation, mechanical ventilation including high frequency oscillation ventilation is the main method. But it is partial unuseful.

Inclusion Criteria:

1. infant less than 28 days
2. diagnosis of ARDS
3. informed parental consent has been obtained

Exclusion Criteria:

1. major congenital malformations or complex congenital heart disease
2. transferred out of the neonatal intensive care unit without treatment