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The study was conducted to investigate the metabolic effects of three different calcium compounds in healthy adults.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| calcium phosphate | Experimental | Pentacalcium hydroxy-triphosphate (Ca5(PO4)3OH) was incorporated in wholemeal and crispy wafer bread in order to achieve a additional calcium intake of 1000 mg/d. |
|
| Tricalcium Phosphate | Experimental | β-tricalcium phosphate (Ca3(PO4)2) as incorporated in wholemeal and crispy wafer bread in order to achieve a additional calcium intake of 1000 mg/d. |
|
| Calcium carbonate | Experimental | Calcium carbonate (CaCO3) was incorporated in wholemeal and crispy wafer bread in order to achieve a additional calcium intake of 1000 mg/d. |
|
| Placebo | Active Comparator | Wholemeal and crispy wafer bread without additional calcium additive. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| calcium phosphate | Dietary Supplement |
| ||
| Tricalcium Phosphate |
| Measure | Description | Time Frame |
|---|---|---|
| Serum mineral concentration | Calcium and Phosphate (and others) concentration in serum. | after 4 weeks of each intervention |
| Stool mineral concentration | Calcium and Phosphate concentration (and others) in stool from a three day stool collection | after 4 weeks of each intervention |
| Urine mineral concentration | Calcium and Phosphate concentration (and others) in urine from a three day urine collection | after 4 weeks of each intervention |
| Lipids in blood | Lipids and lipoprotein concentration in serum. | after 4 weeks of each intervention |
| Sterols | Neutrals sterols and bile acids in stool from a three day stool collection | after 4 weeks of each intervention |
| Dietary intake | Evaluation of the dietary intake using a three day weighed dietary record. | after 4 weeks of each intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Gerhard Jahreis, Prof. Dr. | Friedrich Schiller University Jena, Institute of Nutrition | Principal Investigator |
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| ID | Term |
|---|---|
| C020243 | calcium phosphate |
| C018392 | tricalcium phosphate |
| D002119 | Calcium Carbonate |
| ID | Term |
|---|---|
| D017610 | Calcium Compounds |
| D007287 | Inorganic Chemicals |
| D002254 | Carbonates |
| D002255 | Carbonic Acid |
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| Dietary Supplement |
|
| Calcium carbonate | Dietary Supplement |
|
| Placebo | Dietary Supplement |
|
| D017554 |
| Carbon Compounds, Inorganic |
| D008903 | Minerals |