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to evalute the effect inguinal and subinguinal approach of varicoceclectomy on semen parameter for patients complaining of varicocele with normal semen parameter (pain is the main complaint)
the varicocele is defined as dilated and incompetent veins within the pampiniform plexus of spermatic cord. varicocele has been described as the most common surgically correctable cause of male subinfertility.this is a disease that devolops during puberty when both endocrine and exocrine function of the testicle dramatically increases, along with testicular blood flow. varicocele only rarely detected in boys less than 10 years. left sided varicocle found in 15% of healthy young men.incontrast, the incidence in sub fertile men approaches 40% bilateral varicocele is uncommon in healthy men (less than 10%) but palpated in 20% in sub fertile men. in-general varicocele don't spontaneously regress. an accurate physical examination remain the corner stone of varicocele diagnosis.
several anatomic features contribute to the predominance of left sided varicocele is the left intrnal spermatic vein longer than the right and it typically joins the left renal vein at a right angle.as result of this character higher venous pressures fair transmited to the left spermatic vein and result in reterograde reflux of blood.
varicocle are associated with testicular atrophhy and varicocle correction can reverse atrophy in adolececnt. there is strong evidence affect semen quality it can cause abnormalties in concentration, motility and morphology.main defect is the motility.
indication of varicocelectomy:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| high inguinal approch | Patients undergoing high inguinal varicocelectomy with normal pre operative semen parameters, post operative semen analysis parameters will be recorded |
| |
| subinguinal approch | Patients undergoing subinguinal varicocelectomy with normal pre operative semen parameters, post operative semen analysis parameters will be recorded |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High inguinal Varicocelectomy | Procedure | Semen parameters after high inguinal varicocelectomy will be collected |
|
| Measure | Description | Time Frame |
|---|---|---|
| Semen analysis | Motility morphology concentration | 3months |
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Inclusion Criteria:
Exclusion Criteria:
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Male patients undergoing varicocelectomy while having normal semen parameters (doing surgery for other reasons eg. pain)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Abdelrahman M Abdelkader | Contact | 01068336396 | abdelrahmanmohamed.aa@gmail.com | |
| Mohamed A Osman, professor | Contact | 01062226639 | 0882315760 | osman@aun.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Ehab O Ahmed | unaffiliation | Study Director |
| Mohamed I Taha | unaffiliation | Study Chair |
| Ahmed k mohamed |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assuit Medical School | Asyut | Assuit | 71621 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28846314 | Background | Leslie SW, Sajjad H, Siref LE. Varicocele. 2023 Nov 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK448113/ | |
| 28834886 | Background | Wu X, Liu Q, Zhang R, Wang W, Gao Y. Therapeutic efficacy and safety of laparoscopic surgery versus microsurgery for varicocele of adult males: A meta-analysis. Medicine (Baltimore). 2017 Aug;96(34):e7818. doi: 10.1097/MD.0000000000007818. |
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| ID | Term |
|---|---|
| D014646 | Varicocele |
| D007246 | Infertility |
| D010146 | Pain |
| ID | Term |
|---|---|
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
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| Subinguinal varicocelectomy | Procedure | Semen parameters after subinguinal Varicocelectomy will be collected |
|
| unaffiliation |
| Study Director |
| 28817895 | Background | Canning DA. Re: Sperm Concentration and Forward Motility are Not Correlated with Age in Adolescents with an Idiopathic Varicocele and Symmetrical Testicular Volumes. J Urol. 2017 Sep;198(3):472. doi: 10.1016/j.juro.2017.06.068. Epub 2017 Jun 20. No abstract available. |
| 8725614 | Background | Schmidt B. Membranes in artificial organs. Artif Organs. 1996 May;20(5):375-80. doi: 10.1111/j.1525-1594.1996.tb04519.x. |
| 28718159 | Background | Sedaghatpour D, Berookhim BM. The Role of Varicocele in Male Factor Subfertility. Curr Urol Rep. 2017 Sep;18(9):73. doi: 10.1007/s11934-017-0713-8. |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |