Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Chinese Academy of Sciences | OTHER_GOV |
Not provided
Not provided
Not provided
Not provided
Glaucoma is currently the second leading cause of irreversible blindness in the world. Our study intends to combine clinical data of glaucoma patients in Zhongshan Ophthalmic Center with Artificial Intelligence techniques to create programs that can screen and diagnose glaucoma.
Glaucoma is currently the second leading cause of irreversible blindness in the world, which brings heavy burden to human society. Compared to other ocular diseases, diagnostic process of glaucoma is complicated depends on multiple test results, including visual field test, OCT, etc. How to diagnose glaucoma correctly and fast has always been a hot topic in glaucoma researches. Artificial intelligence is used to study and develop theories and methods that can help simulate and extend human intelligence, which has been utilized in a lot of research fields such as automatic drive and medicine. The study intends to combine clinical data of glaucoma patients in Zhongshan Ophthalmic Center with Artificial Intelligence techniques to create programs that can screen and diagnose glaucoma.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Glaucoma patients | Glaucoma patients will take visual field test and OCT imaging of optic nerve area. All of these data will be collected as source of machine learning. |
| |
| Non-glaucoma participants | Non-glaucoma participants will take visual field test and OCT imaging of optic nerve area. All of these data will be collected as source of machine learning. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Visual field and OCT tests | Diagnostic Test | Visual field test and OCT are commonly used essential tests to make accurate diagnosis of glaucoma. Algorithms to classify Visual field and OCT tests would both be developed and verified. |
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy of diagnosis by artificial intelligence algorithm | Accuracy of diagnosis by artificial intelligence algorithm and compare this result with glaucoma specialists | from August 2017 to February 2021 |
| Measure | Description | Time Frame |
|---|---|---|
| Sensitivity of diagnosis by artificial intelligence algorithm | Sensitivity of diagnosis by artificial intelligence algorithm | from August 2017 to February 2021 |
| Specificity of diagnosis by artificial intelligence algorithm |
Not provided
Inclusion Criteria:
Exclusion Criteria:
1. unable to complete visual field test
Not provided
Not provided
Not provided
Not provided
Anyone who can complete visual field test and have BCVA>0.1 can be enrolled. We will collect visual field test result and OCT images of both glaucoma and non-glaucoma patients.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Xiulan Zhang, Doctor | Sun Yat-sen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zhongshan Ophthalmic Center | Guangzhou | Guangdong | 510000 | China |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D005901 | Glaucoma |
| ID | Term |
|---|---|
| D009798 | Ocular Hypertension |
| D005128 | Eye Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D014794 | Visual Fields |
| ID | Term |
|---|---|
| D009799 | Ocular Physiological Phenomena |
Not provided
Not provided
Not provided
Not provided
Not provided
Specificity of diagnosis by artificial intelligence algorithm
| from August 2017 to February 2021 |
| 27395766 | Result | Asaoka R, Murata H, Iwase A, Araie M. Detecting Preperimetric Glaucoma with Standard Automated Perimetry Using a Deep Learning Classifier. Ophthalmology. 2016 Sep;123(9):1974-80. doi: 10.1016/j.ophtha.2016.05.029. Epub 2016 Jul 7. |